教授/博士生导师,国家自然科学基金优秀青年基金获得者(2021)
办公室:n.a.
电 话:n.a.
E-mail: cmse.gaoy@buct.edu.cn
课题组网站:https://www.x-mol.com/groups/gao-lab
研究领域:
1.活体内超分子组装方法学
2.超分子组装体的动态变构
3.药物递送与生物正交前药
4.动态光散射小角中子散射
2008.09-2011.07 美国布兰戴斯大学,博士
2005.09-2008.08 香港科技大学
2001.09-2005.06 南京大学,学士2023.03 - 至 今 北京化工大学,bwin必赢中国官网 教授,博士生导师
2015.11-2023.02 国家纳米科学中心 研究员,博士生导师
2013.03-2015.03 美国国立卫生研究院 博士后
2011.10-2013.02 美国布兰戴斯大学化学系 博士后
从事超分子自组装及生物纳米材料方向的研究。发表论文60余篇,包括Sci.Adv.,Nat. Commun.,Adv. Mater.,JACS.,Chem. Soc. Rev.等,引用5500余次。已授权9项中国专利,1项美国专利。获NRC RAP Award,主持中科院“率先行动”百人计划(择优支持),国家重点研发计划课题,基金委面上、优秀青年基金等项目。
1. Chen, J.#, Zhang, P.#, Zhao, Y., Zhao, J., Wu, X., Zhang, R., Cha, R., Yao, Q., Gao, Y.* “Nitroreductase-Instructed Supramolecular Assemblies for Microbiome Regulation to Enhance Colorectal Cancer Treatments” Sci. Adv. 2022, 8, eadd2789.
2. Tian, F.#, Yang, M.#, Yao, Q., Song, J., He, J., Shi, X.*, Gao, Y.* “Kinetic Selectivity Dictates the Construction of Cancer Cell-Targeting Enzyme Instructed Supramolecular Assemblies” Nano Today, 2022, 47, 101658.
3. Yao, Q., Gao, S., Wu, C., Lin, T.*, Gao, Y.* “Enzymatic non-covalent synthesis of supramolecular assemblies as a general platform for bioorthogonal prodrugs activation to combat drug resistance” Biomaterials, 2021, 277, 121119.
4. Huang, Z.#, Liu, Y.#, Wang, L., Ali, A., Yao, Q., Jiang, X.*, Gao, Y.* “Supramolecular Assemblies mimicking Neutrophil Extracellular Traps for MRSE Infection Control” Biomaterials, 2020, 253, 120124.
5. Yao, Q.#, Wang, C.#, Fu, M., Dai, L.*, Li, J.*, Gao, Y.* “Dynamic Detection of Active Enzyme Instructed Supramolecular Assemblies In Situ via Super-Resolution Microscopy” ACS Nano, 2020, 14, 4882-4889.
6. Yao, Q., Huang, Z., Liu, D., Chen, J., Gao, Y.* “Enzyme-Instructed Supramolecular Self-Assembly with Anticancer Activity” Adv. Mater., 2019, 31, 1804814.
7. Yao, Q., Lin, F., Fan, X., Wang, Y., Liu, Y., Liu, Z., Jiang, X., Chen, P.*, Gao, Y.* “Synergistic Enzymatic and Bioorthogonal Reactions for Selective Prodrug Activation in Living Systems” Nat. Commun., 2018, 9, 5032.
8. Huang, P.*, Gao, Y.*, Lin, J., Hu, H., Liao, H., Yan, X., Tang, Y., Jin, A., Song, J., Niu, G., Zhang, G., Horkay, F., Chen, X.* “Tumor-Specific Formation of Enzyme-Instructed Supramolecular Self-Assemblies as Cancer Theranostics” ACS Nano, 2015, 9, 9517–9527
9. Gao, Y.; Shi, J. F.; Yuan, D.; Xu, B.* “Imaging enzyme-triggered self-assembly of small molecules inside live cells” Nat. Commun., 2012, 3, 1033.
10. Gao, Y.; Kuang, Y.; Guo, Z.-F.; Guo, Z. H.; Krauss, I. J.; Xu, B.* “Enzyme-Instructed Molecular Self-assembly Confers Nanofibers and A Supramolecular Hydrogel of Taxol Derivative” J. Am. Chem. Soc., 2009, 131, 13576-13577.